Spontaneous Tumor Lysis Syndrome Secondary to Small-Cell Neuroendocrine Carcinoma of Unknown Origin: A Rare Case Report and Literature Review

Spontaneous Tumor Lysis Syndrome Secondary to Small-Cell Neuroendocrine Carcinoma of Unknown Origin: A Rare Case Report and Literature Review

Spontaneous tumor lysis syndrome (STLS), in the absence of prior chemo or radiation therapy, is rare with solid tumors. Here, we present a case of STLS secondary to a small-cell neuroendocrine tumor of unknown origin in a 66-year-old female patient who presented with abdominal discomfort. Computed t...

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Main Authors: Phyo Thazin Myint, Hifza Waheed Butt, Taha Alrifai, Carlos Marin
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2019/6375693
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spelling doaj-3260224a45fc4048af0268c3b74fc0952020-11-25T01:45:00ZengHindawi LimitedCase Reports in Oncological Medicine2090-67062090-67142019-01-01201910.1155/2019/63756936375693Spontaneous Tumor Lysis Syndrome Secondary to Small-Cell Neuroendocrine Carcinoma of Unknown Origin: A Rare Case Report and Literature ReviewPhyo Thazin Myint0Hifza Waheed Butt1Taha Alrifai2Carlos Marin3Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL, USADepartment of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL, USADepartment of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL, USADepartment of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL, USASpontaneous tumor lysis syndrome (STLS), in the absence of prior chemo or radiation therapy, is rare with solid tumors. Here, we present a case of STLS secondary to a small-cell neuroendocrine tumor of unknown origin in a 66-year-old female patient who presented with abdominal discomfort. Computed tomography (CT) abdomen showed a large tumor mass with peritoneal metastasis, and she developed renal failure from STLS, resulting in the need for hemodialysis. Due to the progressive deterioration and the comorbidities, she opted for comfort care. Timely recognition and intervention of STLS is critical. Further studies evaluating STLS in solid tumor patients are recommended.http://dx.doi.org/10.1155/2019/6375693
collection DOAJ
language English
format Article
sources DOAJ
author Phyo Thazin Myint
Hifza Waheed Butt
Taha Alrifai
Carlos Marin
spellingShingle Phyo Thazin Myint
Hifza Waheed Butt
Taha Alrifai
Carlos Marin
Spontaneous Tumor Lysis Syndrome Secondary to Small-Cell Neuroendocrine Carcinoma of Unknown Origin: A Rare Case Report and Literature Review
Case Reports in Oncological Medicine
author_facet Phyo Thazin Myint
Hifza Waheed Butt
Taha Alrifai
Carlos Marin
author_sort Phyo Thazin Myint
title Spontaneous Tumor Lysis Syndrome Secondary to Small-Cell Neuroendocrine Carcinoma of Unknown Origin: A Rare Case Report and Literature Review
title_short Spontaneous Tumor Lysis Syndrome Secondary to Small-Cell Neuroendocrine Carcinoma of Unknown Origin: A Rare Case Report and Literature Review
title_full Spontaneous Tumor Lysis Syndrome Secondary to Small-Cell Neuroendocrine Carcinoma of Unknown Origin: A Rare Case Report and Literature Review
title_fullStr Spontaneous Tumor Lysis Syndrome Secondary to Small-Cell Neuroendocrine Carcinoma of Unknown Origin: A Rare Case Report and Literature Review
title_full_unstemmed Spontaneous Tumor Lysis Syndrome Secondary to Small-Cell Neuroendocrine Carcinoma of Unknown Origin: A Rare Case Report and Literature Review
title_sort spontaneous tumor lysis syndrome secondary to small-cell neuroendocrine carcinoma of unknown origin: a rare case report and literature review
publisher Hindawi Limited
series Case Reports in Oncological Medicine
issn 2090-6706
2090-6714
publishDate 2019-01-01
description Spontaneous tumor lysis syndrome (STLS), in the absence of prior chemo or radiation therapy, is rare with solid tumors. Here, we present a case of STLS secondary to a small-cell neuroendocrine tumor of unknown origin in a 66-year-old female patient who presented with abdominal discomfort. Computed tomography (CT) abdomen showed a large tumor mass with peritoneal metastasis, and she developed renal failure from STLS, resulting in the need for hemodialysis. Due to the progressive deterioration and the comorbidities, she opted for comfort care. Timely recognition and intervention of STLS is critical. Further studies evaluating STLS in solid tumor patients are recommended.
url http://dx.doi.org/10.1155/2019/6375693
work_keys_str_mv AT phyothazinmyint spontaneoustumorlysissyndromesecondarytosmallcellneuroendocrinecarcinomaofunknownoriginararecasereportandliteraturereview
AT hifzawaheedbutt spontaneoustumorlysissyndromesecondarytosmallcellneuroendocrinecarcinomaofunknownoriginararecasereportandliteraturereview
AT tahaalrifai spontaneoustumorlysissyndromesecondarytosmallcellneuroendocrinecarcinomaofunknownoriginararecasereportandliteraturereview
AT carlosmarin spontaneoustumorlysissyndromesecondarytosmallcellneuroendocrinecarcinomaofunknownoriginararecasereportandliteraturereview
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