Retinal nerve fiber layer thickness predicts CSF amyloid/tau before cognitive decline.

Retinal nerve fiber layer thickness predicts CSF amyloid/tau before cognitive decline.

<h4>Background</h4>Alzheimer's disease (AD) pathology precedes symptoms and its detection can identify at-risk individuals who may benefit from early treatment. Since the retinal nerve fiber layer (RNFL) is depleted in established AD, we tested whether its thickness can predict whet...

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Bibliographic Details
Main Authors: Samuel Asanad, Michele Fantini, William Sultan, Marco Nassisi, Christian M Felix, Jessica Wu, Rustum Karanjia, Fred N Ross-Cisneros, Abhay P Sagare, Berislav V Zlokovic, Helena C Chui, Janice M Pogoda, Xianghong Arakaki, Alfred N Fonteh, Alfredo A Sadun, Michael G Harrington
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232785

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