A novel technique for the in vivo imaging of autoimmune diabetes development in the pancreas by two-photon microscopy.

A novel technique for the in vivo imaging of autoimmune diabetes development in the pancreas by two-photon microscopy.

Type 1 diabetes (T1D) is characterized by the immune-mediated destruction of beta cells in the pancreas. Little is known about the in vivo dynamic interactions between T cells and beta cells or the kinetic behavior of other immune cell subsets in the pancreatic islets. Utilizing multiphoton microsco...

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Bibliographic Details
Main Authors: Ken Coppieters, Marianne M Martinic, William B Kiosses, Natalie Amirian, Matthias von Herrath
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3009738?pdf=render

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