Central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) following concurrent chemoradiotherapy for nasopharyngeal carcinoma

Central pontine myelinolysis (CPM) and extrapontine myelinolysis (EPM) following concurrent chemoradiotherapy for nasopharyngeal carcinoma

Central pontine myelinolysis (CPM) is a disease that may present with coma, quadriplegia, or no symptoms at all. It is an iatrogenic demyelinating disease caused most frequently by overzealous correction of chronic hyponatremia and excessive swings in serum osmolality. Lesions can also occur outside...

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Bibliographic Details
Main Authors: Chen-Hui Chong, Guan-Min Lai, Jen-Tsun Lin
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-06-01
Series:Journal of Cancer Research and Practice
Subjects:
Central pontine myelinosis
Extrapontine myelinosis
Nasopharyngeal carcinoma
Hyponatremia
Concurrent chemoradiotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2311300616300143
Description
Summary:Central pontine myelinolysis (CPM) is a disease that may present with coma, quadriplegia, or no symptoms at all. It is an iatrogenic demyelinating disease caused most frequently by overzealous correction of chronic hyponatremia and excessive swings in serum osmolality. Lesions can also occur outside the pons as extrapontine myelinolysis (EPM). Herein we have reported a case of CPM and EPM in a patient after chemoradiotherapy for recurrent nasopharyngeal carcinoma.
ISSN:2311-3006

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