STUDY OF ANTIHERPETIC ACTIVITY OF LADY'S MANTLE (<i>ALCHEMILLA VULGARIS</i> L.) EXTRACTS

• Main Authors: N. A. Mazurkova, T. A. Kukushkina, G. I. Vysochina, Z. B. Ibragimova, I. E. Lobanova, E. I. Filippova, O. Yu. Mazurkov, E. V. Makarevich, L. N. Shishkina, A. P. Agafonov
• Format: Article
• Language: Russian
• Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
• Series: Разработка и регистрация лекарственных средств
• Subjects: extracts of lady's mantle (alchemilla vulgaris l.); antiviral activity; herpes simplex virus
• Online Access: https://www.pharmjournal.ru/jour/article/view/230
• ISSN: 2305-2066; 2658-5049

The article presents information on the distribution, on the use in traditional medicine, the chemical composition of plant material, pharmacological study of lady's mantle (Alchemilla vulgaris L.), as well as the results of a study in culture Vero cell toxicity and antiviral properties of aqueous solutions of dry ethanol extract of the aerial parts and the ethyl acetate extract of the roots of lady's mantle, growing in Western Siberia, in respect of the herpes simplex virus. It is shown that the extracts derived from both aerial parts and roots of plants have on the Vero cell culture antiviral activity against herpes simplex virus of 1 and 2-type.