Acetic acid treatment in S.cerevisiae creates significant energy deficiency and nutrient starvation that is dependent on the activity of mitochondrial transcriptional complex Hap2-3-4-5.

Acetic acid treatment in S.cerevisiae creates significant energy deficiency and nutrient starvation that is dependent on the activity of mitochondrial transcriptional complex Hap2-3-4-5.

Metabolic pathways play an indispensable role in supplying cellular systems with energy and molecular building blocks for growth, maintenance and repair and are tightly linked with lifespan and systems stability of cells. For optimal growth and survival cells rapidly adopt to environmental changes....

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Bibliographic Details
Main Authors: Ana eKitanovic, Felix eBonowski, Florian eHeigwer, Peter eRuoff, Igor eKitanovic, Christin eUngewiss, Stefan eWölfl
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-09-01
Series:Frontiers in Oncology
Subjects:
Acetic Acid
Apoptosis
metabolic control
growth dynamic
Hap4p
intracellular pH homeostasis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00118/full

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