Brain-targeted delivery of trans-activating transcriptor-conjugated magnetic PLGA/lipid nanoparticles.

Brain-targeted delivery of trans-activating transcriptor-conjugated magnetic PLGA/lipid nanoparticles.

Magnetic poly (D,L-lactide-co-glycolide) (PLGA)/lipid nanoparticles (MPLs) were fabricated from PLGA, L-α-phosphatidylethanolamine (DOPE), 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-amino (polyethylene glycol) (DSPE-PEG-NH2), and magnetic nanoparticles (NPs), and then conjugated to trans-acti...

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Bibliographic Details
Main Authors: Xiangru Wen, Kai Wang, Ziming Zhao, Yifang Zhang, Tingting Sun, Fang Zhang, Jian Wu, Yanyan Fu, Yang Du, Lei Zhang, Ying Sun, YongHai Liu, Kai Ma, Hongzhi Liu, Yuanjian Song
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4154764?pdf=render

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