Evaluating the Effect of Protein A Signal Peptide on Extracellular Expression of Recombinant Hirudin in E.Coli

Evaluating the Effect of Protein A Signal Peptide on Extracellular Expression of Recombinant Hirudin in E.Coli

Abstract         Background and Objective: Hirudin is an anticoagulant polypeptide secreted from the salivary glands of leeches. Recombinant hirudin is a strong anticoagulant agent in arterial and venous thrombosis. The aim of this study was to evaluate the effect of inserting protein A signal pept...

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Bibliographic Details
Main Authors: Parisa Bakhshi, Massoud Saidijam, Delavar Shahbazzadeh, Nazanin Mohajerani, Hassan Mirzahoseini
Format: Article
Language:English
Published: Golestan University of Medical Sciences 2015-11-01
Series:Medical Laboratory Journal
Subjects:
hirudin
desirudin
protein sorting signals.
Online Access:http://mlj.goums.ac.ir/article-1-797-en.html

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