A unified censored normal regression model for qPCR differential gene expression analysis.
Reverse transcription quantitative polymerase chain reaction (RT-qPCR) is considered as the gold standard for accurate, sensitive, and fast measurement of gene expression. Prior to downstream statistical analysis, RT-qPCR fluorescence amplification curves are summarized into one single value, the qu...
Main Authors: | Peter Pipelers, Lieven Clement, Matthijs Vynck, Jan Hellemans, Jo Vandesompele, Olivier Thas |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5560691?pdf=render |
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