Improved Quantity and In Vivo Function of Islets Isolated by Reduced Pressure-Controlled Injection of Collagenase in a Rat Model

Improved Quantity and In Vivo Function of Islets Isolated by Reduced Pressure-Controlled Injection of Collagenase in a Rat Model

In islet transplantation, insufficient yield is a major obstacle to one-donor/one-recipient transplant. Collagenase, which is injected via a pancreatic duct to separate islets from acini, can so easily distribute into the islet core that it may result in disruption of islets. The purpose of this stu...

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Bibliographic Details
Main Authors: Shiri Li, Tetsuya Sakai, Yasuyuki Suzuki, Tadahiro Goto, Tomohiro Tanaka, Takuro Yoshikawa, Keitaro Kakinoki, Yasuki Tanioka, Ippei Matsumoto, Yasuhiro Fujino, Yoshikazu Kuroda
Format: Article
Language:English
Published: SAGE Publishing 2007-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000007783464957

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