miR-21 mimic blocks obesity in mice: A novel therapeutic option

miR-21 mimic blocks obesity in mice: A novel therapeutic option

MicroRNAs (miRNAs) are promising drug targets for obesity and metabolic disorders. Recently, miRNA mimics are providing a unique mechanism of action that guides the process for drug development and sets out the context of their therapeutic application. miRNA (miR)-21 expression in white adipose tiss...

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Bibliographic Details
Main Authors: Said Lhamyani, Adriana-Mariel Gentile, Rosa M. Giráldez-Pérez, Mónica Feijóo-Cuaresma, Silvana Yanina Romero-Zerbo, Mercedes Clemente-Postigo, Hatem Zayed, Wilfredo Oliva Olivera, Francisco Javier Bermúdez-Silva, Julián Salas, Carlos López Gómez, Abdelkrim Hmadcha, Nabil Hajji, Gabriel Olveira, Francisco J. Tinahones, Rajaa El Bekay
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
obesity
miR-21
adipose tissue
thermogenesis
browning
brown adipose tissue
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121001608

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