Ferulic acid attenuates non-alcoholic steatohepatitis by reducing oxidative stress and inflammation through inhibition of the ROCK/NF-κB signaling pathways

Ferulic acid (FA) is a natural polyphenol compound existing in many plants. The purpose of this study was to investigate the effect of FA on non-alcoholic steatohepatitis (NASH) induced by high-cholesterol and high-fat diet (HCHF) and its possible mechanism. Rats were fed HCHF for 12 weeks to establ...

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Bibliographic Details
Main Authors: Ziheng Wei, Yurun Xue, Yucong Xue, Jie Cheng, Guoping Lv, Li Chu, Zhihong Ma, Shengjiang Guan
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861321000487