Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions
The Membrane-Proximal External Region (MPER) of the HIV Env gp41 subunit is a target for broadly neutralizing antibodies. Here, the authors apply super-resolution stimulated emission depletion (STED) microscopy on single virions and provide insights into how the MPER epitope is recognized.
Bibliographic Details
| Main Authors: |
Pablo Carravilla,
Jakub Chojnacki,
Edurne Rujas,
Sara Insausti,
Eneko Largo,
Dominic Waithe,
Beatriz Apellaniz,
Taylor Sicard,
Jean-Philippe Julien,
Christian Eggeling,
José L. Nieva |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2019-01-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-018-07962-9
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