Chlamydia trachomatis co-opts the FGF2 signaling pathway to enhance infection.

The molecular details of Chlamydia trachomatis binding, entry, and spread are incompletely understood, but heparan sulfate proteoglycans (HSPGs) play a role in the initial binding steps. As cell surface HSPGs facilitate the interactions of many growth factors with their receptors, we investigated th...

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Bibliographic Details
Main Authors: Jung Hwa Kim, Shaobo Jiang, Cherilyn A Elwell, Joanne N Engel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3188521?pdf=render