New pre-clinical evidence of anti-inflammatory effect and safety of a substituted fluorophenyl imidazole

New pre-clinical evidence of anti-inflammatory effect and safety of a substituted fluorophenyl imidazole

Acute Respiratory Distress Syndrome (ARDS) is an inflammatory condition with high mortality rates, and there is still no pharmacological approach with proven effectiveness. In the past few years, several imidazole small molecules have been developed to treat conditions in which inflammation plays a...

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Bibliographic Details
Main Authors: Marcus Vinicius Pereira dos Santos Nascimento, Antonio Carlos Mattar Munhoz, Bruno Matheus De Campos Facchin, Eduarda Fratoni, Thaís Andreia Rossa, Marcus Mandolesi Sá, Carlo Cosimo Campa, Elisa Ciraolo, Emilio Hirsch, Eduardo Monguilhott Dalmarco
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Imidazole
Inflammation
In vivo
NF-κB
p38 MAPK
ARDS
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218386803

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