New Ratios for Performance Improvement for Identifying Acyl-CoA Dehydrogenase Deficiencies in Expanded Newborn Screening: A Retrospective Study

New Ratios for Performance Improvement for Identifying Acyl-CoA Dehydrogenase Deficiencies in Expanded Newborn Screening: A Retrospective Study

Some success in identifying acyl-CoA dehydrogenase (ACAD) deficiencies before they are symptomatic has been achieved through tandem mass spectrometry. However, there has been several challenges that need to be confronted, including excess false positives, the occasional false negatives and indicator...

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Bibliographic Details
Main Authors:	Benjing Wang, Qin Zhang, Ang Gao, Qi Wang, Jun Ma, Hong Li, Ting Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-09-01
Series:	Frontiers in Genetics
Subjects:	C4/C5DC+C6-OH C8/C14:1 C14:1/C16-OH short chain acyl-CoA dehydrogenase deficiency medium chain acyl-CoA dehydrogenase deficiency very long chain acyl-CoA dehydrogenase deficiency
Online Access:	https://www.frontiersin.org/article/10.3389/fgene.2019.00811/full

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