Intervention for early diabetic nephropathy by mesenchymal stem cells in a preclinical nonhuman primate model

Intervention for early diabetic nephropathy by mesenchymal stem cells in a preclinical nonhuman primate model

Abstract Background Diabetic nephropathy (DN) is one of the most severe chronic diabetic complications and the main cause of end-stage renal disease. Chronic inflammation plays a key role in the development of DN. However, few treatment strategies are available; therefore, new and effective strategi...

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Main Authors: Xingxing An, Guangneng Liao, Younan Chen, Ai Luo, Jingping Liu, Yujia Yuan, Lan Li, Lichuan Yang, Hong Wang, Fang Liu, Guang Yang, Shounan Yi, Yuanmin Li, Jingqiu Cheng, Yanrong Lu
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Stem Cell Research & Therapy
Subjects:
Diabetic nephropathy
Nonhuman primate model
Mesenchymal stem cells
Inflammation
SGLT2 inhibition
Online Access:https://doi.org/10.1186/s13287-019-1401-z

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