ORGINAL PAPER<br>Modulation of the tissue defense system by squalene in cyclophosphamide induced toxicity in rats
Introduction: Antineoplastic drug, Cyclophosphamide (CP), is a widely used drug that causes toxicity through its metabolites, phosphoramide mustard and acrolein. Squalene (SQ), an intermediate in the cholesterol metabolism has antioxidant and membrane stabilizing property. In the present study, the...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Termedia Publishing House
2006-06-01
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Series: | Archives of Medical Science |
Subjects: | |
Online Access: | http://www.termedia.pl/magazine.php?magazine_id=19&article_id=6200&magazine_subpage=FULL_TEXT |