Hormonal regulation of glycine decarboxylase and its relationship to oxidative stress

Abstract In both humans and rodent models, circulating glycine levels are significantly reduced in obesity, glucose intolerance, type II diabetes, and non‐alcoholic fatty liver disease. The glycine cleavage system and its rate‐limiting enzyme, glycine decarboxylase (GLDC), is a major determinant of...

Full description

Bibliographic Details
Main Authors: Ruta Jog, Guohua Chen, Jian Wang, Todd Leff
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.14991