Hormonal regulation of glycine decarboxylase and its relationship to oxidative stress
Abstract In both humans and rodent models, circulating glycine levels are significantly reduced in obesity, glucose intolerance, type II diabetes, and non‐alcoholic fatty liver disease. The glycine cleavage system and its rate‐limiting enzyme, glycine decarboxylase (GLDC), is a major determinant of...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-08-01
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Series: | Physiological Reports |
Subjects: | |
Online Access: | https://doi.org/10.14814/phy2.14991 |