Fiber type-specific nitric oxide protects oxidative myofibers against cachectic stimuli.
Oxidative skeletal muscles are more resistant than glycolytic muscles to cachexia caused by chronic heart failure and other chronic diseases. The molecular mechanism for the protection associated with oxidative phenotype remains elusive. We hypothesized that differences in reactive oxygen species (R...
Main Authors: | Zengli Yu, Ping Li, Mei Zhang, Mark Hannink, Jonathan S Stamler, Zhen Yan |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-05-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2361191?pdf=render |
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