Predicting capsule fill weight from in-situ powder density measurements using terahertz reflection technology

The manufacturing of the majority of solid oral dosage forms is based on the densification of powder. A good understanding of the powder behavior is therefore essential to assure high quality drug products. This is particularly relevant for the capsule filling process, where the powder bulk density...

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Bibliographic Details
Main Authors: Sandra Stranzinger, Eva Faulhammer, Jingyi Li, Runqiao Dong, J. Axel Zeitler, Stefano Biserni, Vittorio Calzolari, Johannes G. Khinast, Daniel Markl
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:International Journal of Pharmaceutics: X
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156718300045