TNFα Affects Ciliary Beat Response to Increased Viscosity in Human Pediatric Airway Epithelium

TNFα Affects Ciliary Beat Response to Increased Viscosity in Human Pediatric Airway Epithelium

In airway epithelium, mucociliary clearance (MCC) velocity depends on the ciliary beat frequency (CBF), and it is affected by mucus viscoelastic properties. Local inflammation induces secretion of cytokines (TNFα) that can alter mucus viscosity; however airway ciliated cells have an autoregulatory m...

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Bibliographic Details
Main Authors: Claudia González, Karla Droguett, Mariana Rios, Noam A. Cohen, Manuel Villalón
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2016/3628501

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