Does Impaired O2 Delivery During Exercise Accentuate Central and Peripheral Fatigue in Patients with Coexistent COPD-CHF?

Does Impaired O2 Delivery During Exercise Accentuate Central and Peripheral Fatigue in Patients with Coexistent COPD-CHF?

Impairment in oxygen (O2) delivery to the central nervous system (brain) and skeletal locomotor muscle during exercise has been associated with central and peripheral neuromuscular fatigue in healthy humans. From a clinical perspective, impaired tissue O2 transport is a key pathophysiological mechan...

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Bibliographic Details
Main Authors:	Mayron F. Oliveira, Joel T. J. Zelt, Joshua H. Jones, Daniel M. Hirai, Dennis E. O'Donnell, Samuel eVerges, J. Alberto eNeder
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-01-01
Series:	Frontiers in Physiology
Subjects:	Respiratory Muscles oxygenation skeletal muscle chronic obstructive pulmonary disease chronic heart failure
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00514/full

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