The Effect of Glycyrrhetinic Acid on Pharmacokinetics of Cortisone and Its Metabolite Cortisol in Rats

The Effect of Glycyrrhetinic Acid on Pharmacokinetics of Cortisone and Its Metabolite Cortisol in Rats

The purpose of this paper is to study pharmacokinetics of cortisone (E) and its metabolite cortisol (F) in rats after administration of glycyrrhetinic acid (GA) and cortisone. Healthy male SD rats were randomized to be given 20 mg/kg E or E combined with 10 mg/kg GA. Blood samples were collected at...

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Bibliographic Details
Main Authors:	Dan Lin, Wei Sun, Zhe Wang, Lian-Guo Chen, Xiao-Le Chen, Shuang-Hu Wang, Wan-Shu Li, Ren-Shan Ge, Guo-Xin Hu
Format:	Article
Language:	English
Published:	Hindawi Limited 2012-01-01
Series:	Journal of Biomedicine and Biotechnology
Online Access:	http://dx.doi.org/10.1155/2012/856324

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