The Impact of Tumor Eco-Evolution in Renal Cell Carcinoma Sampling

The Impact of Tumor Eco-Evolution in Renal Cell Carcinoma Sampling

Malignant tumors behave dynamically as cell communities governed by ecological principles. Massive sequencing tools are unveiling the true dimension of the heterogeneity of these communities along their evolution in most human neoplasms, clear cell renal cell carcinomas (CCRCC) included. Although in...

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Bibliographic Details
Main Authors: Estíbaliz López-Fernández, José I. López
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Cancers
Subjects:
clear cell renal cell carcinoma
tumor evolution
tumor ecology
intratumor heterogeneity
multisite tumor sampling
targeted therapy
Online Access:https://www.mdpi.com/2072-6694/10/12/485

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