Sulfated Zirconia-Catalyzed Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (DHPMs) Under Solventless Conditions: Competitive Multicomponent Biginelli vs. Hantzsch Reactions

Sulfated Zirconia-Catalyzed Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (DHPMs) Under Solventless Conditions: Competitive Multicomponent Biginelli vs. Hantzsch Reactions

The catalytic ability of ZrO2/SO42- to promote solventless three-componentcondensation reactions of a diversity of aromatic aldehydes, urea or thoiurea and ethylacetoacetate was studied. Products resulting from Hantzsch and/or Biginelli multi-component reactions are obtained in the presence of solid...

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Bibliographic Details
Main Authors: Guillermo Negrón-Silva, Eduardo González-Zamora, Victor H. Lara-Corona, Leticia Lomas-Romero, Deyanira Angeles-Beltrán
Format: Article
Language:English
Published: MDPI AG 2006-10-01
Series:Molecules
Subjects:
Biginelli reaction
Hantzsch reaction
multicomponent reactions
1
4- dihydropyridines
dihydropyrimidinones
solventless reactions.
Online Access:http://www.mdpi.com/1420-3049/11/10/731/

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http://www.mdpi.com/1420-3049/11/10/731/

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