Interleukin-4 regulates eomesodermin in CD8+ T cell development and differentiation.

Interleukin (IL)-4 is a cytokine classically associated with CD4(+) T helper type 2 differentiation, but has been recently shown to also be required for the development of CD8(+) innate-like lymphocytes. CD8(+) innate-like lymphocytes are non-conventional lymphocytes that exhibit characteristics typ...

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Bibliographic Details
Main Authors: Shannon A Carty, Gary A Koretzky, Martha S Jordan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4160212?pdf=render