Randomized test-treatment studies with an outlook on adaptive designs

Randomized test-treatment studies with an outlook on adaptive designs

Abstract Background Diagnostic accuracy studies aim to examine the diagnostic accuracy of a new experimental test, but do not address the actual merit of the resulting diagnostic information to a patient in clinical practice. In order to assess the impact of diagnostic information on subsequent trea...

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Bibliographic Details
Main Authors: Amra Hot, Patrick M. Bossuyt, Oke Gerke, Simone Wahl, Werner Vach, Antonia Zapf
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Medical Research Methodology
Subjects:
Accuracy
Adaptive design
Diagnostic research
Patient-relevant outcome
RCT
Sample size
Online Access:https://doi.org/10.1186/s12874-021-01293-y

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