Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids

Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids

The biosynthesis of pyridine rings is still poorly understood. Here the authors propose a biosynthetic pathway for pyridine-containing rubrolones, which is characterized by a non-enzymatic condensation and cyclization of the pyridine moiety.

Bibliographic Details
Main Authors: Yijun Yan, Jing Yang, Zhiyin Yu, Mingming Yu, Ya-Tuan Ma, Li Wang, Can Su, Jianying Luo, Geoffrey P. Horsman, Sheng-Xiong Huang
Format: Article
Language:English
Published: Nature Publishing Group 2016-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13083
Description
Summary:The biosynthesis of pyridine rings is still poorly understood. Here the authors propose a biosynthetic pathway for pyridine-containing rubrolones, which is characterized by a non-enzymatic condensation and cyclization of the pyridine moiety.
ISSN:2041-1723

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