Chagas disease, adipose tissue and the metabolic syndrome

Chagas disease, adipose tissue and the metabolic syndrome

Trypanosoma cruzi infection of the adipose tissue of mice triggers the local expression of inflammatory mediators and a reduction in the expression of the adipokine adiponectin. T. cruzi can be detected in adipose tissue by PCR 300 days post-infection. Infection of cultured adipocytes results in inc...

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Bibliographic Details
Main Authors: Fnu Nagajyothi, Mahalia S Desruisseaux, Louis M Weiss, Streamson Chua, Chris Albanese, Fabiana S Machado, Lisia Esper, Michael P Lisanti, Mauro M Teixeira, Philipp E Scherer, Herbert B Tanowitz
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2009-07-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
adipose tissue
adipocyte
adiponectin
Trypanosoma cruzi
Chagas disease
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000900028

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