Type 2 Diabetes Mellitus and Alzheimer’s Disease: Role of Insulin Signalling and Therapeutic Implications

Type 2 Diabetes Mellitus and Alzheimer’s Disease: Role of Insulin Signalling and Therapeutic Implications

In the last two decades, numerous in vitro studies demonstrated that insulin receptors and theirs downstream pathways are widely distributed throughout the brain. This evidence has proven that; at variance with previous believes; insulin/insulin-like-growth-factor (IGF) signalling plays a crucial ro...

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Bibliographic Details
Main Authors: Andrea Tumminia, Federica Vinciguerra, Miriam Parisi, Lucia Frittitta
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
insulin receptor
insulin signalling
neurodegenerative disorders
Alzheimer’s disease
type 2 diabetes mellitus
Online Access:https://www.mdpi.com/1422-0067/19/11/3306

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