Anti-nociceptive effects of Sedum Lineare Thunb. on spared nerve injury-induced neuropathic pain by inhibiting TLR4/NF-κB signaling in the spinal cord in rats

Anti-nociceptive effects of Sedum Lineare Thunb. on spared nerve injury-induced neuropathic pain by inhibiting TLR4/NF-κB signaling in the spinal cord in rats

Neuropathic pain is still a critical public health problem worldwide. Thereby, the search for novel and more effective strategies against neuropathic pain is urgently considered. It is known that neuroinflammation plays a crucial role in the pathogenesis of neuropathic pain. SedumLineare Thunb. (SLT...

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Bibliographic Details
Main Authors: Xin-ying Wang, Hai-juan Ma, Meng Xue, Ya-lan Sun, An Ren, Meng-qi Li, Zhi-hua Huang, Cheng Huang
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
SedumLineare Thunb
Neuropathic pain
Microglial activation
Cytokine
HMGB1
TLR4/NF-κB signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220314086

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