Preparation and Ultrasonic Imaging Investigation of Perfluoropentane-Filled Polylactic Acid Nanobubbles As a Novel Targeted Ultrasound Contrast Agent

Preparation and Ultrasonic Imaging Investigation of Perfluoropentane-Filled Polylactic Acid Nanobubbles As a Novel Targeted Ultrasound Contrast Agent

In the study reported here, polylactic acid (PLLA) polymer was synthesized using stannous octoate (Sn(Oct)2) and N-(t-butoxycarbonyl) ethanolamine (EABoc) as the catalyst and the initiator, respectively. The selected PLLA polymer with proper molecular weight was used to prepare nanobubbles encapsula...

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Bibliographic Details
Main Authors: Ruolei Xiao, Zhiwei Zhao, Jiajuan Chen, Liu He, Huili Wang, Lingping Huang, Binhua Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Materials
Subjects:
polylactic acid
nanobubbles
contrast agent
in vivo ultrasound imaging
in vitro acoustic behavior
Online Access:https://www.frontiersin.org/articles/10.3389/fmats.2020.549002/full

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