Topological Polar Surface Area, Molecular Weight, and Rotatable Bond Count Account for the Variations in the Inhibitory Potency of Antimycotics against Microsporum canis

Topological Polar Surface Area, Molecular Weight, and Rotatable Bond Count Account for the Variations in the Inhibitory Potency of Antimycotics against Microsporum canis

Multivariate statistical models were utilized to identify the interaction between the inhibitory activity and the molecular properties of the different antimycotics against Microsporum canis. Information on the inhibitory potency against M. canis and molecular properties of antifungal agents were...

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Bibliographic Details
Main Authors: Derick Erl P. Sumalapao, Nelson R. Villarante, Josephine D. Agapito, Abubakar S. Asaad, Nina G. Gloriani
Format: Article
Language:English
Published: Journal of Pure and Applied Microbiology 2020-03-01
Series:Journal of Pure and Applied Microbiology
Subjects:
dermatophytes
fungal infections
molecular descriptors
multivariate data analysis
regression equation
Online Access:https://microbiologyjournal.org/topological-polar-surface-area-molecular-weight-and-rotatable-bond-count-account-for-the-variations-in-the-inhibitory-potency-of-antimycotics-against-microsporum-canis/

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