Green Tea Polyphenol (−)-Epigallocatechin Gallate (EGCG) Attenuates Neuroinflammation in Palmitic Acid-Stimulated BV-2 Microglia and High-Fat Diet-Induced Obese Mice

Green Tea Polyphenol (−)-Epigallocatechin Gallate (EGCG) Attenuates Neuroinflammation in Palmitic Acid-Stimulated BV-2 Microglia and High-Fat Diet-Induced Obese Mice

Obesity is closely associated with neuroinflammation in the hypothalamus, which is characterized by over-activated microglia and excessive production of pro-inflammatory cytokines. The present study was aimed at elucidating the effects of (−)-epigallocatechin gallate (EGCG) on palmitic aci...

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Bibliographic Details
Main Authors: Limin Mao, Danielle Hochstetter, Liyun Yao, Yueling Zhao, Jihong Zhou, Yuefei Wang, Ping Xu
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
tea polyphenols
saturated fatty acids
obesity
hypothalamus
inflammation
Online Access:https://www.mdpi.com/1422-0067/20/20/5081

Internet

https://www.mdpi.com/1422-0067/20/20/5081

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