Effect of complex of ozone and laserotherapy on prooxidant-antioxidant balance in blood of patients with lung tuberculosis in the intensive phase chemotherapy

• Main Authors: O. O. Otchych, K. D. Mazhak, D. I. Sanahurskyi
• Format: Article
• Language: English
• Published: Львівський національний університет імені Івана Франка 2014-09-01
• Series: Біологічні студії
• Subjects: lipid peroxidation; antioxidant protection; molecule of middle mass; chemo-ozone-laserotherapy; tuberculosis
• Online Access: http://publications.lnu.edu.ua/journals/index.php/biology/article/view/180

The influence of complex of ozone- and lazerotherapy the level of endogenous intoxication, lipid peroxidation and activity of antioxidant enzymes in patients with destructive pulmonary tuberculosis in the intensive phase of chemotherapy was investigated. Analysis of the results of study conducted on the use of different modes of ozone- and laserotherapy found that an integrated treatment in combination with chemotherapy has a pronounced positive effect on the balance of prooxidant-antioxidant processes in patients with newly diagnosed pulmonary tuberculosis, compared with single chemotherapy. It was found that the greatest increase in activity of antioxidant enzymes and the level of inhibition of lipid peroxidation in erythrocyte membranes occurred in the conditions of exposure modes: with increasing ozone (step 2 mg/l) and decreasing ozone concentration of 2 to 12 mg/l ↑↓ number of procedures + internally laser irradiation of blood with frequency modulation 100 kHz and internal laser irradiation of blood with frequency modulation 100 kHz + ozone 2 to 12 mg/l ↑↓ (step 2 mg/l), under the background of chemotherapy (CT).