GSTM1 Copy Number Is Not Associated With Risk of Kidney Failure in a Large Cohort

GSTM1 Copy Number Is Not Associated With Risk of Kidney Failure in a Large Cohort

Deletion of glutathione S-transferase µ1 (GSTM1) is common in populations and has been asserted to associate with chronic kidney disease progression in some research studies. The association needs to be validated. We estimated GSTM1 copy number using whole exome sequencing data in the DiscovEHR coho...

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Bibliographic Details
Main Authors: Yanfei Zhang, Waleed Zafar, Dustin N. Hartzel, Marc S. Williams, Adrienne Tin, Alex R. Chang, Ming Ta Michael Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Genetics
Subjects:
GSTM1
kidney failure
copy number
large cohort
electronic health records
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00765/full

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