Morphological state of aorta in the fetuses and newborns suffered from chronic intrauterine hypoxia (experimental research)

The cardiovascular system in newborns with chronic hypoxia is affected in 40–70%. Aim. To investigate morphological state of aorta in the fetuses and newborns suffered from chronic intrauterine hypoxia. Methods and results. Aortic wall was investigated with modern morphological methods in 34 l...

Full description

Bibliographic Details
Main Author: O. V. Kaluzhina
Format: Article
Language:English
Published: Zaporozhye State Medical University 2015-04-01
Series:Patologìâ
Subjects:
Online Access:http://pat.zsmu.edu.ua/article/view/42818/39222
Description
Summary:The cardiovascular system in newborns with chronic hypoxia is affected in 40–70%. Aim. To investigate morphological state of aorta in the fetuses and newborns suffered from chronic intrauterine hypoxia. Methods and results. Aortic wall was investigated with modern morphological methods in 34 laboratory animals in order to identify the morphological features of the fetuses and newborns’ vessel affected by this pathogenic factor. It was established that chronic hypoxia leads to endothelial trophics deterioration, its flattening, dystrophic processes with following cells desquamation, density reduction of smooth muscle cells, thickening of the intima-media. Conclusion. It shows alterative-sclerotic changes in aorta in cases with chronic hypoxia influence.
ISSN:2306-8027
2310-1237