Progranulin regulates neuronal outgrowth independent of Sortilin

Progranulin regulates neuronal outgrowth independent of Sortilin

<p>Abstract</p> <p>Background</p> <p>Progranulin (PGRN), a widely secreted growth factor, is involved in multiple biological functions, and mutations located within the PGRN gene (<it>GRN</it>) are a major cause of frontotemporal lobar degeneration with TDP-...

Full description

Bibliographic Details
Main Authors: Gass Jennifer, Lee Wing C, Cook Casey, Finch Nicole, Stetler Caroline, Jansen-West Karen, Lewis Jada, Link Christopher D, Rademakers Rosa, Nykjær Anders, Petrucelli Leonard
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Molecular Neurodegeneration
Subjects:
Progranulin
Sortilin
Neuronal outgrowth
Frontotemporal lobar degeneration
Neurotrophic factor
Online Access:http://www.molecularneurodegeneration.com/content/7/1/33

Internet

http://www.molecularneurodegeneration.com/content/7/1/33

Similar Items