A drug-sensitive genetic network masks fungi from the immune system.
Fungal pathogens can be recognized by the immune system via their beta-glucan, a potent proinflammatory molecule that is present at high levels but is predominantly buried beneath a mannoprotein coat and invisible to the host. To investigate the nature and significance of "masking" this mo...
Main Authors: | Robert T Wheeler, Gerald R Fink |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2006-04-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC1447670?pdf=render |
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