A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions

A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions

SWI/SNF complexes regulate chromatin architecture and gene expression. Here the authors report the RNA interactome of SMARCB1-containing SWI/SNF complexes, showing the function of SMARCB1-interacting long noncoding RNA SWINGN in transcriptional activation of GAS6 and a set of SWI/SNF target genes.

Bibliographic Details
Main Authors: Elena Grossi, Ivan Raimondi, Enrique Goñi, Jovanna González, Francesco P. Marchese, Vicente Chapaprieta, José I. Martín-Subero, Shuling Guo, Maite Huarte
Format: Article
Language:English
Published: Nature Publishing Group 2020-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14623-3

Internet

https://doi.org/10.1038/s41467-020-14623-3

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