Functional complexity of the Leishmania granuloma and the potential of in silico modelling

AbstractIn human and canine visceral leishmaniasis and in various experimental models of this disease, host resistance is strongly linked to efficient granuloma development. However, it is unknown exactly how the granuloma microenvironment executes an effective antileishmanial response. Recent studi...

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Bibliographic Details
Main Authors: John eMoore, Daniel eMoyo, Lynette eBeattie, Paul eAndrews, Jon eTimmis, Paul eKaye
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00035/full