Palliative radiation therapy for symptomatic advance breast cancer

Abstract In this study, we evaluated the effectiveness of palliative breast radiation therapy (RT), with single fraction RT compared with fractionated RT. Our study showed that both RT fractionation schemas provide palliation. Single fraction RT allowed for treatment with minimal interference with s...

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Main Authors: Galia Jacobson, Orit Kaidar-Person, Ory Haisraely, Shira Galper, Tatiana Rabin, Ilanit Dromi Shahadi, Yaacov Richard Lawrence, Zvi Symon, Merav Akiva Ben-David
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84872-9
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spelling doaj-3118800d30944007896ec44a19f819f52021-03-11T12:25:59ZengNature Publishing GroupScientific Reports2045-23222021-03-011111610.1038/s41598-021-84872-9Palliative radiation therapy for symptomatic advance breast cancerGalia Jacobson0Orit Kaidar-Person1Ory Haisraely2Shira Galper3Tatiana Rabin4Ilanit Dromi Shahadi5Yaacov Richard Lawrence6Zvi Symon7Merav Akiva Ben-David8Radiation Oncology, Chaim Sheba Medical CenterRadiation Oncology, Chaim Sheba Medical CenterRadiation Oncology, Chaim Sheba Medical CenterRadiation Oncology, Chaim Sheba Medical CenterSackler School of Medicine, Tel Aviv UniversityRadiation Oncology, Chaim Sheba Medical CenterRadiation Oncology, Chaim Sheba Medical CenterRadiation Oncology, Chaim Sheba Medical CenterSackler School of Medicine, Tel Aviv UniversityAbstract In this study, we evaluated the effectiveness of palliative breast radiation therapy (RT), with single fraction RT compared with fractionated RT. Our study showed that both RT fractionation schemas provide palliation. Single fraction RT allowed for treatment with minimal interference with systemic therapy, whereas fractionated RT provided a more durable palliative response. Due to equivalent palliative response, at our institution we have increasingly been providing single fraction RT palliation during the COVID-19 pandemic.https://doi.org/10.1038/s41598-021-84872-9
collection DOAJ
language English
format Article
sources DOAJ
author Galia Jacobson
Orit Kaidar-Person
Ory Haisraely
Shira Galper
Tatiana Rabin
Ilanit Dromi Shahadi
Yaacov Richard Lawrence
Zvi Symon
Merav Akiva Ben-David
spellingShingle Galia Jacobson
Orit Kaidar-Person
Ory Haisraely
Shira Galper
Tatiana Rabin
Ilanit Dromi Shahadi
Yaacov Richard Lawrence
Zvi Symon
Merav Akiva Ben-David
Palliative radiation therapy for symptomatic advance breast cancer
Scientific Reports
author_facet Galia Jacobson
Orit Kaidar-Person
Ory Haisraely
Shira Galper
Tatiana Rabin
Ilanit Dromi Shahadi
Yaacov Richard Lawrence
Zvi Symon
Merav Akiva Ben-David
author_sort Galia Jacobson
title Palliative radiation therapy for symptomatic advance breast cancer
title_short Palliative radiation therapy for symptomatic advance breast cancer
title_full Palliative radiation therapy for symptomatic advance breast cancer
title_fullStr Palliative radiation therapy for symptomatic advance breast cancer
title_full_unstemmed Palliative radiation therapy for symptomatic advance breast cancer
title_sort palliative radiation therapy for symptomatic advance breast cancer
publisher Nature Publishing Group
series Scientific Reports
issn 2045-2322
publishDate 2021-03-01
description Abstract In this study, we evaluated the effectiveness of palliative breast radiation therapy (RT), with single fraction RT compared with fractionated RT. Our study showed that both RT fractionation schemas provide palliation. Single fraction RT allowed for treatment with minimal interference with systemic therapy, whereas fractionated RT provided a more durable palliative response. Due to equivalent palliative response, at our institution we have increasingly been providing single fraction RT palliation during the COVID-19 pandemic.
url https://doi.org/10.1038/s41598-021-84872-9
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