Copy Number Alterations and Methylation in Ewing's Sarcoma

Ewing's sarcoma is the second most common bone malignancy affecting children and young adults. The prognosis is especially poor in metastatic or relapsed disease. The cell of origin remains elusive, but the EWS-FLI1 fusion oncoprotein is present in the majority of cases. The understanding of th...

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Bibliographic Details
Main Authors: Mona S. Jahromi, Kevin B. Jones, Joshua D. Schiffman
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Sarcoma
Online Access:http://dx.doi.org/10.1155/2011/362173

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