Cholesterol feeding strongly reduces hepatic VLDL-triglyceride production in mice lacking the liver X receptor αs⃞

Cholesterol feeding strongly reduces hepatic VLDL-triglyceride production in mice lacking the liver X receptor αs⃞

The oxysterol-activated nuclear receptor liver X receptor α (LXRα) has been implicated in the control of both cholesterol and fatty acid metabolism. In this study, we have evaluated the effects of excess dietary cholesterol on hepatic cholesterol metabolism, lipogenesis, and VLDL production in homoz...

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Bibliographic Details
Main Authors: Jelske N. van der Veen, Rick Havinga, Vincent W. Bloks, Albert K. Groen, Folkert Kuipers
Format: Article
Language:English
Published: Elsevier 2007-02-01
Series:Journal of Lipid Research
Subjects:
nuclear receptors
cholesterol absorption
ATP binding cassette transporter g5
ATP binding cassette transporter g8
biliary cholesterol secretion
lipogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520436697

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http://www.sciencedirect.com/science/article/pii/S0022227520436697

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