The Effect of Inulin on Lifespan, Related Gene Expression and Gut Microbiota in InRp5545/TM3 Mutant Drosophila melanogaster: A Preliminary Study

The Effect of Inulin on Lifespan, Related Gene Expression and Gut Microbiota in InRp5545/TM3 Mutant Drosophila melanogaster: A Preliminary Study

Inulin is considered an efficient prebiotic and is beneficial for metabolic diseases via promoting intestinal probiotic enrichment and the metabolites of short-chain fatty acids (SCFAs). However, the effect of inulin on patients with InR deficiencies has seldom been reported. In this study, the life...

Full description

Bibliographic Details
Main Authors:	Yuling Dong, Hao Sun, Weichao Yang, Shuang Ma, Beibei Du, Hui Xu
Format:	Article
Language:	English
Published:	MDPI AG 2019-03-01
Series:	Nutrients
Subjects:	inulin Drosophila melanogaster lifespan insulin/insulin-like growth factor (IGF)-like signalling (IIS) pathway gut microbiota
Online Access:	http://www.mdpi.com/2072-6643/11/3/636

Similar Items

Insulin-Like Signalling Influences the Coordination of Larval Hemocyte Number with Body Size in Drosophila melanogaster
by: Daniel Bakopoulos, et al.
Published: (2020-07-01)

Impact of<i> </i>Probiotic Combination in <i>InR</i><sup>[E19]</sup>/TM2 <i>Drosophila melanogaster</i> on Longevity, Related Gene Expression, and Intestinal Microbiota: A Preliminary Study
by: Shuang Ma, et al.
Published: (2020-07-01)

The main actors involved in extending the invertebrate life span
by: E Ottaviani, et al.
Published: (2014-02-01)

The main actors involved in extending the invertebrate life span
by: E Ottaviani, et al.
Published: (2014-02-01)

The Metabolic Response to Infection With Wolbachia Implicates the Insulin/Insulin-Like-Growth Factor and Hypoxia Signaling Pathways in Drosophila melanogaster
by: Denni Currin-Ross, et al.
Published: (2021-03-01)

Drosophila Insulin-Like Peptides DILP2 and DILP5 Differentially Stimulate Cell Signaling and Glycogen Phosphorylase to Regulate Longevity
by: Stephanie Post, et al.
Published: (2018-05-01)

RME-1 is required for lifespan extension and increased resistance to stresses associated with decreased insulin/IGF-1-like signaling in Caenorhabditis elegans
by: Kim Chul-Kyu, et al.
Published: (2017-01-01)

THE GENETIC MECHANISMS OF THE INFLUENCE OF THE LIGHT REGIME ON THE LIFESPAN OF DROSOPHILA MELANOGASTER
by: Olga eShostal, et al.
Published: (2013-01-01)

Functional Implications of Drosophila insulin-like peptides in metabolism, aging and dietary restriction
by: Kavitha ekannan, et al.
Published: (2013-10-01)

The <em>C. elegans</em> insulin-like peptides (ILPs)
by: Yohei Matsunaga, et al.
Published: (2018-10-01)

Evidence of dietary protein restriction regulating pupation height, development time and lifespan in Drosophila melanogaster
by: Sudhakar Krittika, et al.
Published: (2019-06-01)

Lifespan extension induced by caffeine in Caenorhabditis elegans is partially dependent on adenosine signaling
by: Jessika Cristina Bridi, et al.
Published: (2015-12-01)

Phytosterols and inulin-enriched soymilk increases glucagon-like peptide-1 secretion in healthy men: double-blind randomized controlled trial, subgroup study
by: Noppadol Kietsiriroje, et al.
Published: (2018-11-01)

Amyloid-β peptides slightly affect lifespan or antimicrobial peptide gene expression in Drosophila melanogaster
by: Mikhail V. Shaposhnikov, et al.
Published: (2020-10-01)

Using Drosophila to discover mechanisms underlying type 2 diabetes
by: Ronald W. Alfa, et al.
Published: (2016-04-01)

Modulated Expression of the Protein Kinase GSK3 in Motor and Dopaminergic Neurons Increases Female Lifespan in Drosophila melanogaster
by: Mikhail V. Trostnikov, et al.
Published: (2020-06-01)

Microphysiometry Studies of Rapid Binding of Insulin-Like Growth Factor I by Parental and Transfected Mammary Epithelial Cell Lines
by: Robinson, Rose Marie
Published: (2014)

Morphological and functional effects of insulin signaling and the bHLH transcription factor Dimmed on different neuron types in Drosophila
by: Liu, Yiting
Published: (2016)

Aging Regulated Through a Stability Model of Insulin/Insulin Growth Factor Receptor Function
by: Marc Tatar
Published: (2021-03-01)

Insulin-like growth factor II gene Apa I polymorphism is not associated with endometriosis susceptibility
by: Yao-Yuan Hsieh, et al.
Published: (2004-01-01)

The role of oleuropein against nanocomposite toxicity in fruit fly: evidence for lifespan extension
by: Tuğba Atici, et al.
Published: (2021-04-01)

The Roles of the IGF Axis in the Regulation of the Metabolism: Interaction and Difference between Insulin Receptor Signaling and IGF-I Receptor Signaling
by: Tomoko Okuyama, et al.
Published: (2021-06-01)

Disrupting Insulin and IGF Receptor Function in Cancer
by: Jingran Cao, et al.
Published: (2021-01-01)

Myricetin-Mediated Lifespan Extension in Caenorhabditis elegans Is Modulated by DAF-16
by: Wim Wätjen, et al.
Published: (2013-06-01)

Insulin-like Growth Factors (IGFs) and their binding proteins (IGFBPs) as biomarkers of catabolism
by: Nedić Olgica, et al.
Published: (2007-01-01)

Polyandry enhances offspring viability with survival costs to mothers only when mating exclusively with virgin males in Drosophila melanogaster
by: Sergio Castrezana, et al.
Published: (2017-09-01)

Chain length‐dependent inulin alleviates diet‐induced obesity and metabolic disorders in mice
by: Liangkui Li, et al.
Published: (2021-07-01)

A link between phenotypic robustness and life expectancy in Drosophila melanogaster
by: L. P. Zakharenko, et al.
Published: (2017-12-01)

Evolutionary Analysis of the Insulin-Relaxin Gene Family from the Perspective of Gene and Genome Duplication Events
by: Olinski, Robert Piotr
Published: (2007)

The Sexual Dimorphism of Dietary Restriction Responsiveness in Caenorhabditis elegans
by: Sakiko Honjoh, et al.
Published: (2017-12-01)

Modifying Effects of Glucose and Insulin/Insulin-Like Growth Factors on Colon Cancer Cells
by: Şeyda Berk, et al.
Published: (2021-07-01)

Ferulic Acid Supplementation Increases Lifespan and Stress Resistance via Insulin/IGF-1 Signaling Pathway in <i>C. elegans</i>
by: Hui Li, et al.
Published: (2021-04-01)

Prognostic and Therapeutic Roles of the Insulin Growth Factor System in Glioblastoma
by: Elena Tirrò, et al.
Published: (2021-02-01)

The insulin/IGF signaling cascade modulates SUMOylation to regulate aging and proteostasis in Caenorhabditis elegans
by: Lorna Moll, et al.
Published: (2018-11-01)

The oestrogen receptor in porcine granulosa cells
by: Bains, Harvinder
Published: (2002)

Understanding IGF-II Action through Insights into Receptor Binding and Activation
by: Andrew J. Blyth, et al.
Published: (2020-10-01)

Insulin-like growth factor binding proteins: a structural perspective
by: Briony eForbes, et al.
Published: (2012-03-01)

Somatotropic Axis Regulation Unravels the Differential Effects of Nutritional and Environmental Factors in Growth Performance of Marine Farmed Fishes
by: Jaume Pérez-Sánchez, et al.
Published: (2018-11-01)

Cord blood level of insulin-like growth factor-1 and IGF binding protein-3 in monochorionic twins
by: Ru-Jeng Teng, et al.
Published: (2015-04-01)

The genetic dissection of the fruitless gene's functions during embryogenesis in Drosophila melanogaster
by: Song, Ho-Juhn
Published: (2012)

Cannot write session to /tmp/vufind_sessions/sess_o0ssrmbeb6mc02knjq4eive43r