Annexin II Light Chain p11 Interacts With ENaC to Increase Functional Activity at the Membrane

Annexin II Light Chain p11 Interacts With ENaC to Increase Functional Activity at the Membrane

The epithelial Na+ channel (ENaC) provides for Na+ absorption in various types of epithelia including the kidney, lung, and colon where ENaC is localized to the apical membrane to enable Na+ entry into the cell. The degree of Na+ entry via ENaC largely depends on the number of active channels locali...

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Bibliographic Details
Main Authors: Tanya T. Cheung, Noor A. S. Ismail, Rachel Moir, Nikhil Arora, Fiona J. McDonald, Steven B. Condliffe
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Physiology
Subjects:
epithelial
sodium
channel
p11
annexin II
protein interaction
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00007/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00007/full

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