Phase II Study of Biweekly Plitidepsin as Second-Line Therapy for Advanced or Metastatic Transitional Cell Carcinoma of the Urothelium
The objective of this exploratory, open-label, single-arm, phase II clinical trial was to evaluate plitidepsin (5 mg/m2) administered as a 3-hour continuous intravenous infusion every two weeks to patients with locally advanced/metastatic transitional cell carcinoma of the urothelium who relapsed/pr...
Main Authors: | Sergio Szyldergemajn, Jean P. Droz, Sonia Extremera, Patrick Schöffski, Joan Carles Galceran, Enrique Gallardo, Stephane Culine, Aude Fléchon, Herlinde Dumez |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2009-09-01
|
Series: | Marine Drugs |
Subjects: | |
Online Access: | http://www.mdpi.com/1660-3397/7/3/451/ |
Similar Items
-
Plitidepsin Has a Safe Cardiac Profile: A Comprehensive Analysis
by: Carmen Kahatt, et al.
Published: (2011-06-01) -
Plitidepsin: design, development, and potential place in therapy
by: Alonso-Álvarez S, et al.
Published: (2017-01-01) -
c-Jun N-Terminal Kinase Phosphorylation Is a Biomarker of Plitidepsin Activity
by: Alberto Muñoz, et al.
Published: (2013-05-01) -
Phase II Randomized Study of Plitidepsin (Aplidin), Alone or in Association with L-carnitine, in Patients with Unresectable Advanced Renal Cell Carcinoma
by: Patrick Schöffski, et al.
Published: (2009-03-01) -
Trabectedin and Plitidepsin: Drugs from the Sea that Strike the Tumor Microenvironment
by: Carlos M. Galmarini, et al.
Published: (2014-01-01)