ABCA7 expression is regulated by cellular cholesterol through the SREBP2 pathway and associated with phagocytosis

ABCA7 expression is regulated by cellular cholesterol through the SREBP2 pathway and associated with phagocytosis

ABCA7 is highly homologous to ABCA1 and mediates cellular cholesterol and phospholipid release by apolipoproteins when transfected in vitro. However, expression of ABCA7 was downregulated by increased cellular cholesterol while ABCA1 was upregulated, and the results were consistent by forced express...

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Bibliographic Details
Main Authors:	Noriyuki Iwamoto, Sumiko Abe-Dohmae, Ryuichiro Sato, Shinji Yokoyama
Format:	Article
Language:	English
Published:	Elsevier 2006-09-01
Series:	Journal of Lipid Research
Subjects:	ATP binding cassette transporter A7 ATP binding cassette transporter A1 cholesterol high density lipoprotein sterol-responsive/regulatory element sterol-responsive/regulatory element binding protein
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520434583

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