Aldose reductase C-106T gene polymorphism in type 2 diabetics with microangiopathy in Iranian individuals

Aldose reductase C-106T gene polymorphism in type 2 diabetics with microangiopathy in Iranian individuals

Background: Aldose reductase (AR) is the rate-limiting enzyme in the glucose metabolism, which has been implicated in the pathogenesis of diabetic microvascular complications (MVCs). Frequent C-106T polymorphism in the promoter of the AR gene may change the expression of the gene. Aims: The aim of t...

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Bibliographic Details
Main Authors: Majid Reza Sheikh Rezaee, Ahmad Ahmadzadeh Amiri, Mohammad Bagher Hashemi-Soteh, Fatemeh Daneshvar, Roghaye Emady-Jamaly, Reza Jafari, Behyar Soleimani, Hamed Haghiaminjan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Indian Journal of Endocrinology and Metabolism
Subjects:
Aldose reductase genotypes
C-106T polymorphisms
diabetic microvascular complications
Online Access:http://www.ijem.in/article.asp?issn=2230-8210;year=2015;volume=19;issue=1;spage=95;epage=99;aulast=Rezaee

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http://www.ijem.in/article.asp?issn=2230-8210;year=2015;volume=19;issue=1;spage=95;epage=99;aulast=Rezaee

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